About Us
International Center for Applied Biological Sciences (ICABS)
ICABS is the genetic laboratory specialized in whole genome sequencing (WGS), and as such sets new standards in the approach to personalized medicine and represents a revolutionary step forward in translational medicine.
To facilitate the integration of Genomics into mainstream diagnostics, we provide a comprehensive range of genetic testing solutions and the flexibility to customize testing to specific indications.
ICABS plays a leading role in providing information on patients' genetic profiles, which enables them to:
- Adjust therapy
- Diagnose rare genetic diseases
- Determine risk for oncological diseases
- Provide personalized therapy
International Center for Applied Biological Sciences (ICABS) offers different clinical genetic testing.
Testing for hereditary disorders, specifically germline mutations, is a pivotal component of genetic diagnostics.
Cancers are caused by somatic mutations that occur in the DNA during lifetime.
This panel is recommended for couples who are planning a pregnancy and want to know if there is a risk of transmitting a genetic disease to the child.
We provide genetic counseling in collaboration with our partner St. Catherine Specialty Hospital.
About Genetic Testing
What Is Genetic Testing?
Genetic testing is a type of diagnostic test that can analyze human DNA, RNA, and chromosomes to detect alterations related to rare diseases. This in turn can confirm or rule out a suspected genetic condition or can also help determine a person’s future chance of developing or passing on a genetic disorder.
Genetic testing has benefits but also has risks and limitations and hence whether to be tested or not is a personal and complex decision.
A specialist or subspecialist in medical genetics can help an individual by providing information about the pros and cons of the test and discuss the social and emotional aspects of the test results. Genetic Counseling is now an important step for any genetic testing service, which we offer in collaboration with our partner St. Catherine Specialty Hospital.
Total number of rare diseases - more than 8000
Genetic cause of rare diseases
80%
Patient without diagnosis
55%
What We Do
Clinical genetic testing options
The International Center for Applied Biological Sciences (ICABS) offers different clinical genetic testing.
High-quality Clinical Genetic Laboratory
Our team of experts in the field of personalized medicine, committed to quality, defines our strength.
Our Latest Case Studies
Our collaboration between the public and private sectors, as well as industry and academia, bring a real impact on patient’s health and healthcare in general.
Osteogenesis imperfecta (OI) is characterized by fractures with minimal or absent trauma, representing a continuum ranging from perinatal lethality through individuals with severe skeletal deformities to nearly asymptomatic individuals with mild predisposition to fractures. Diagnosis of OI is an interdisciplinary task based on family and/or patient history of fractures combined with characteristic physical findings. Radiographic examination reveals fractures of varying ages and stages of healing, wormian bones, and osteopenia. As there is no definitive test for OI, molecular genetic testing by next-generation sequencing (NGS) of COL1A1 and COL1A2 and up to 12 other genes is essential to confirm the genetic background.
Prof. Dragan Primorac, MD, PhD, Pediatrician and Medical Geneticist
Penn State University, State College PA, USA St. Catherine Specialty Hospital, Zagreb, CroatiaBrugada syndrome is a rare hereditary disorder characterized by distinct ECG findings, complex genetics, and a high risk of sudden cardiac death. Recognition of the syndrome is crucial as it represents a paradigm of sudden death tragedy in individuals at the peak of their lives. Notably, Brugada syndrome accounts for more than 20% of sudden cardiac deaths in individuals with structurally normal hearts. Genetics and personalized medicine hold immense potential in the primary prevention, diagnosis, and treatment of Brugada syndrome and sudden cardiac death.
Prof. Joseph Brugada, MD, PhD, Pediatric cardiologist
Cardiovascular Institute, Hospital Clinic, University of Barcelona, Barcelona, SpainCerebrotendinous xanthomatosis (CTX) is a genetic disorder of the cholesterol metabolic pathway, most often associated with variants in the CYP27A1 gene. The dysregulation of cholesterol metabolism results in the accumulation of metabolites such as cholestanol, which has a predilection for neuronal tissue and tendons. The condition is treatable with chenodeoxycholic acid (CDCA), which halts the production of these metabolites. Early diagnosis and treatment initiation in CTX patients is of great importance, as a significant reversal of disease progression can be achieved.
Petar Brlek, MD, PhD Candidate, Medical Genetics Resident
St. Catherine Specialty Hospital, Zagreb, CroatiaWe Will Insure Always Best Results
ICABS follows strict quality control measures and aims to provide comprehensive, accurate, and affordable genetic testing to all. Our Mission is to lead the movement towards early and accurate diagnosis, enabling a better quality of life. We believe that we must be the change we want to see in the world of Diagnostic Genomics.
Assisted by the latest advanced technology and supported by an experienced clinical team, we believe in working with healthcare service providers and researchers to solve the Genomic dilemma.
We Advise to Choose a Right Decision
Our expert team will help you to chose which testing option is best for you.
Our expert team will help you to chose which testing option is best for you.
⮚ Diagnostic Genetic Testing
⮚ Proactive Genetic Testing
⮚ Screening Genetic Testing
⮚ Next-Generation Tumor Genetic Testing
NEWS
Recent Articles and News
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We invite you to join us at the 13th ISABS Conference on Applied Genetics and Mayo Clinic Lectures in Translat...
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The association "EVERYTHING FOR HER" provides support to women with malignant diseases. We had the pleasure of...
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Dr. Parth Shah, Director of Genome Informatics from Dartmouth University visited ICABS and our partner St. Cat...