Have Any Questions
Recently Asked Questions
Candidates for the Genome4All test are:
- Children suffering from rare, inherited diseases for the potential of personalized treatment.
- Children whose disease’s cause has not been identified through conventional clinical examinations.
- Parents planning a family to determine if they carry mutations that could cause serious inherited diseases in their future children.
- Healthy individuals wanting to assess the risk of developing cancer, heart disease, or determine if there is a risk of transmitting genetic diseases to their offspring.
- Healthy individuals with family members affected by various types of cancer, heart diseases, metabolic disorders, etc.
- Afflicted individuals seeking to uncover the genetic cause of their condition and explore the possibility of personalized treatment.
With the Genome4All test, you can find out information about over 20,000 of your genes, which enables timely prevention and diagnosis of the risk of developing the most common diseases today. Also, Genome4All test can help physicians to diagnose rare, hereditary disorders and diseases whose symptoms can appear in early infancy and during adulthood. Besides that, this test enables the testing of over three billion base pairs, which can help physicians to understand the molecular basis of all biological processes, disorders, and diseases.
The Genome4All test enables the detection of hereditary risk for the development of tumors of all organ systems, sudden cardiac death and cardiovascular diseases, obesity, and endocrinological diseases. The test results reveal how your genes affect the metabolism of certain types of food. Using this test, you can create the most effective, personalized diet with the help of our experts.
A large number of cardiovascular diseases, which can lead to sudden cardiac death, have a genetic basis. Within risk groups in the population, in addition to standard clinical treatment following the guidelines of the European Society of Cardiology, it is necessary to perform a genetic screening, which will lead to optimization of treatment, but also a determination of recommendations related to further patient activities.
Each of us may be a healthy carrier of an inherited disease without being aware of it. Knowing your carrier status, especially when anticipating future pregnancies, is crucial medical information for preventing the development of autosomal recessive and X-linked diseases in children whose parents are healthy. If both partners are carriers of the same autosomal recessive disease, there is a 25% chance of transmitting pathogenic gene variants to their children in each pregnancy. In the case of diseases transmitted by the X chromosome, the risk for a healthy mother who is a carrier is 50% of having an affected male child and 50% of having a healthy daughter who is also a carrier. Testing is particularly recommended if there are already family members with inherited diseases, in the case of pregnancy loss without other known causes, in the case of blood-related partnerships, and for individuals belonging to specific ethnic groups.
em Ipsum has been the industry. It has survived not only five centuries, but also the leap into electronic typesetting, remaining essentially unchanged.
Yes. Genome4All test, based on the Whole Genome Sequencing process, is able to detect susceptibility to specific genetic diseases.
In case of a positive test result (when you have been diagnosed with a pathogenic gene variant or a variant of uncertain significance (VUS)), your family members have up to a 50% chance of having the same gene variant. Family testing can identify other family members who are at risk for the same medical condition.
ACMG (American College of Medical Genetics and Genomics) is a professional organization that provides guidelines and standards for the interpretation of genetic variants. The ACMG has developed a classification system for genetic variants based on criteria such as population frequency, computational predictions, functional studies, and segregation data within families. The ACMG classification includes categories like “Pathogenic,” “Likely Pathogenic,” “Uncertain Significance,” “Likely Benign,” and “Benign.”
ACMG Classification:
- Pathogenic: The variant is confirmed or highly likely to cause the disease.
- Likely Pathogenic: The variant has a high probability of causing the disease.
- Uncertain Significance (VUS): The variant’s clinical significance is unclear.
- Likely Benign: The variant is likely not disease-causing.
- Benign: The variant is confirmed not to cause the disease.
These classifications are crucial in clinical genetics for making informed decisions about patient care, risk assessment, and genetic counseling. They help guide medical professionals in understanding the potential impact of genetic variants on an individual’s health.
At ICABS we have our own laboratory and proprietary software experience. This internal infrastructure allows us to develop a very complete service to take care of your needs. We have different types of analysis to suit any level of depth and price.