We are proud to be the first lab in Croatia to have installed System Element AVITI System Sequencing Instrument (Element Biosciences). We are looking forward to start using this NGS system for sequencing to provide a comprehensive range of genetic testing solutions and the flexibility to customize testing to specific indications. This will help us to set new standards in the approach to personalized medicine and represents an important step forward in translational medicine.
Our team published the article “Implementing Whole Genome Sequencing (WGS) in Clinical Practice: Advantages, Challenges, and Future Perspectives” in the scientific journal Cells, as part of the Special Issue Recent Advances in Research on Chromosome Abnormalities and Genomic Disorders. Integrating WGS into standard clinical practice introduces new prospects for personalized medicine and enhanced patient health results, encompassing proactive interventions to deter the onset of complex diseases. Anticipating the future, WGS is poised to become a customary diagnostic instrument in pediatric care, streamlining precise and tailored treatment for children with both monogenic and multifactorial conditions. The assimilation of WGS into clinical practice marks a significant shift in approach, offering optimism for improved outcomes of patient treatments. This potent technology not only heightens diagnostic precision but also unlocks new avenues for personalized therapies.
Article is available online: https://www.mdpi.com/2073-4409/13/6/504
A member of our team co-authored and co-edited the book “Pharmacogenomics in Clinical Practice”, published by Springer Cham. This book offers a practical guide for applications of pharmacogenomics in various medical fields. It includes an overview of the mechanisms involved in membrane transporters and drug-metabolizing enzymes, emphasizing their significance in pharmacogenomics. It also provides detailed guidance on applying these techniques in specialties such as cardiology, gastroenterology, oncology, transplantation surgery, infectious diseases, anesthesia and analgesia, neurology, psychiatry, primary care, and public health. Additionally, it provides clear instructions on utilizing big data technologies and public health databases in routine clinical practice.
“Pharmacogenomics in Clinical Practice” concisely addresses the implementation of pharmacogenomic technologies in routine clinical practice. Therefore, it serves as an excellent current resource for medical practitioners, trainees, and researchers across all medical fields who seek to enhance their understanding and utilization of these techniques.
Book is available as hardcover and ebook (EPUB and PDF): https://link.springer.com/book/10.1007/978-3-031-45903-0
Dr. Parth Shah, Director of Genome Informatics from Dartmouth University visited ICABS and our partner St. Catherine Specialty Hospital and gave an excellent lecture on the future of genomic sequencing and its application in clinical practice. There is no doubt, that genomic medicine is advancing at a rapid pace.